This article discusses the efforts and achievements of Kerala, a state in the south of India, in the fight against Tuberculosis (TB). Despite being the highest TB burden country in the world, India has made significant progress towards TB
elimination, with Kerala leading the way. The state has implemented various innovative strategies, including involving local governments, establishing successful public-private partnerships, improving case management, and rolling
out TB preventive therapy. However, challenges such as high mortality rates, a high percentage of extra-pulmonary TB cases, and limited diagnostic capacity remain. Overall, Kerala is well-positioned to achieve TB elimination, but
continued efforts and interventions are needed to address the remaining challenges.