Research Articles on Tuberculosis from 1940 onwards

New insights into the mechanism of action of pyrazinamide, implications for susceptibilitytesting, and future regimens.
Int J Mycobacteriol. 2016 Dec;5 Suppl 1:S71-S72.
Microbiology. Pyrazinamide--old TB drug finds new target.
Science. 2011 Sep 16;333(6049):1583-4.
Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: classical and new drugs
https://academic.oup.com/jac/issue/66/7
Impact of immunopathology on the antituberculous activity of pyrazinamide.
J Exp Med. 2018 Aug 6;215(8):1975-1986.
A Global Perspective on Pyrazinamide Resistance: Systematic Review and Meta-Analysis.
PLoS One. 2015 Jul 28;10(7):e0133869.
Anti-tubercular Activity of Pyrazinamide is Independent of trans-Translation and RpsA.
Sci Rep. 2017 Jul 21;7(1):6135.
Pyrazinamide Resistance Is Caused by Two Distinct Mechanisms: Prevention of Coenzyme A Depletion and Loss of Virulence Factor Synthesis.
ACS Infect Dis. 2016 Sep 9;2(9):616-626. Epub 2016 Aug 8.
Pyrazinamide Is Active against Mycobacterium tuberculosis Cultures at Neutral pH and LowTemperature.
Antimicrob Agents Chemother. 2016 Jul 22;60(8):4956-60.
Mechanisms of Pyrazinamide Action and Resistance
Microbiol Spectr. 2013; 2(4): 1–12.
Upregulation of the phthiocerol dimycocerosate biosynthetic pathway by rifampin-resistant, rpoBmutant Mycobacterium tuberculosis.
J Bacteriol. 2012 Dec;194(23):6441-52.